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Stephen H Tsang Selected Research

Color Vision Defects (Color Blindness)

11/2022Three-year results of phase I retinal gene therapy trial for CNGA3-mutated achromatopsia: results of a non randomised controlled trial.
7/2021Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy.
1/2019Characterization of Retinal Structure in ATF6-Associated Achromatopsia.
1/2018Gene therapy and genome surgery in the retina.
10/2017Achromatopsia mutations target sequential steps of ATF6 activation.
12/2016Gene and cell-based therapies for inherited retinal disorders: An update.

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Stephen H Tsang Research Topics

Disease

56Retinitis Pigmentosa (Pigmentary Retinopathy)
12/2023 - 03/2007
28Macular Degeneration (Age-Related Maculopathy)
01/2023 - 01/2008
25Retinal Degeneration
08/2023 - 10/2002
23Retinal Diseases
06/2023 - 03/2007
16Atrophy
01/2023 - 11/2008
9Stargardt Disease
03/2024 - 08/2009
9Disease Progression
12/2023 - 07/2017
7Blindness (Hysterical Blindness)
12/2023 - 11/2012
7Choroideremia
01/2022 - 12/2016
7Uveitis
01/2021 - 04/2011
6Night Blindness (Nyctalopia)
01/2023 - 05/2003
6Eye Diseases (Eye Disease)
01/2023 - 03/2015
6Color Vision Defects (Color Blindness)
11/2022 - 12/2016
5Diabetic Retinopathy (Retinopathy, Diabetic)
01/2023 - 11/2009
5Retinal Dystrophies
01/2023 - 05/2009
5Macular Edema
10/2020 - 11/2008
5Inflammation (Inflammations)
01/2020 - 10/2002
5Proliferative Vitreoretinopathy
01/2019 - 04/2011
4Retinal Detachment (Retinal Detachments)
06/2022 - 04/2011
4Neoplasms (Cancer)
11/2017 - 05/2012
3Central Serous Chorioretinopathy
08/2023 - 11/2020
3Posterior Uveitis
01/2019 - 01/2016
3Usher Syndromes (Usher Syndrome)
01/2018 - 12/2016
3Epiretinal Membrane (Epiretinal Membranes)
01/2018 - 08/2017
3Retinoschisis (Retinoschisis, Juvenile)
01/2018 - 08/2015
3Leber Congenital Amaurosis
01/2018 - 05/2009
3Fibrosis (Cirrhosis)
01/2018 - 08/2015
2Acute zonal occult outer retinopathy
08/2023 - 01/2018
2Hypoxia (Hypoxemia)
01/2023 - 01/2016
2Vitamin A Deficiency
01/2023 - 03/2022
2Choroid Diseases
01/2023 - 01/2023
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2023 - 02/2020
2Obesity
03/2022 - 01/2018
2Cone Dystrophy
01/2022 - 01/2021
2Sensorineural Hearing Loss
12/2021 - 01/2018
2Vitelliform Macular Dystrophy
12/2021 - 01/2020
2Doyne honeycomb retinal dystrophy
01/2021 - 01/2018
2Muscular Diseases (Myopathy)
11/2020 - 01/2018
2Retinoblastoma (Glioblastoma, Retinal)
12/2019 - 01/2016
2Mitochondrial Diseases (Mitochondrial Disease)
03/2018 - 01/2018
2MELAS Syndrome (Syndrome, MELAS)
03/2018 - 01/2018
2Bestrophinopathy
01/2018 - 12/2015
2Inborn Genetic Diseases (Disease, Hereditary)
01/2018 - 01/2017
2Enhanced S-Cone Syndrome
01/2018 - 10/2013
2Lactic Acidosis
01/2018 - 01/2018
2Scotoma (Scintillating Scotoma)
01/2018 - 01/2018
2Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy)
01/2018 - 12/2016
2Tuberous Sclerosis (Bourneville's Disease)
10/2016 - 05/2012
2Hamartoma
10/2016 - 05/2012
2Glaucoma
01/2016 - 08/2010
2Seizures (Absence Seizure)
01/2014 - 01/2012
2congenital stationary Night blindness
01/2012 - 03/2007
1Iron Overload
01/2023

Drug/Important Bio-Agent (IBA)

84Retinaldehyde (Retinal)IBA
01/2023 - 06/2008
18Proteins (Proteins, Gene)FDA Link
07/2021 - 04/2011
11Biomarkers (Surrogate Marker)IBA
01/2023 - 11/2009
9Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
12/2023 - 05/2003
8Rhodopsin (Visual Purple)IBA
07/2022 - 05/2012
6Peptide Hydrolases (Proteases)FDA Link
01/2023 - 05/2014
5LipofuscinIBA
01/2023 - 01/2018
3RNA (Ribonucleic Acid)IBA
01/2023 - 01/2016
3Deferoxamine (Desferal)FDA LinkGeneric
01/2023 - 01/2014
3Vitamin A (Retinol)FDA LinkGeneric
01/2023 - 01/2018
3Retinal Pigments (Pigments, Visual)IBA
12/2021 - 04/2010
3Sildenafil Citrate (Viagra)FDA Link
03/2021 - 01/2018
3Carrier Proteins (Binding Protein)IBA
01/2021 - 04/2016
3c-Mer Tyrosine KinaseIBA
12/2020 - 01/2018
3CytokinesIBA
01/2018 - 09/2013
2Acetazolamide (Diamox)FDA LinkGeneric
03/2024 - 08/2015
2Type 6 Cyclic Nucleotide PhosphodiesterasesIBA
12/2023 - 11/2008
2ceramide kinaseIBA
08/2023 - 01/2019
2Metformin (Glucophage)FDA LinkGeneric
01/2023 - 01/2023
2Oxygen (Dioxygen)IBA
01/2023 - 07/2021
2NucleotidesIBA
01/2023 - 10/2017
2Cyclic Nucleotide-Gated Cation ChannelsIBA
01/2023 - 08/2011
21,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2023 - 12/2020
2Chloroquine (Aralen)FDA LinkGeneric
11/2020 - 02/2014
2Mitochondrial DNA (mtDNA)IBA
03/2018 - 01/2018
2CalpainIBA
01/2018 - 08/2015
2Fluorescein (Funduscein)FDA LinkGeneric
01/2018 - 01/2016
2Nonsense Codon (Nonsense Mutation)IBA
05/2017 - 11/2014
2AntibodiesIBA
04/2016 - 01/2016
2Guanosine Monophosphate (5' Guanylic Acid)IBA
01/2014 - 10/2011
2Anticonvulsants (Antiepileptic Drugs)IBA
01/2014 - 01/2012
2VigabatrinFDA Link
01/2014 - 01/2012
2Small Interfering RNA (siRNA)IBA
10/2011 - 08/2011
1AntioxidantsIBA
01/2023
1Antisense OligonucleotidesIBA
01/2023
1IronIBA
01/2023
1Serine (L-Serine)FDA Link
01/2023
1amsonic acid (DAS)IBA
01/2023

Therapy/Procedure

32Therapeutics
06/2023 - 08/2010
8Transplantation
01/2016 - 10/2002
6Lasers (Laser)
01/2016 - 03/2013
3Precision Medicine
01/2022 - 01/2016
3Vitrectomy
01/2018 - 12/2013
2Injections
08/2018 - 12/2017
2Autologous Transplantation
01/2016 - 11/2012
2Stem Cell Transplantation
01/2016 - 11/2012
1Chelation Therapy (Therapy, Chelation)
01/2023